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The medication is indicated for adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

doi: 10.3389/fendo.2026.1709556 Received 23 September 2025 Revised 15 January 2026 Accepted 26 January 2026 Published 11 February 2026 Volume 17 - 2026 Edited by Abdel Halim Harrath, King Saud University, Saudi Arabia Reviewed by Aldo Ferreira-Hermosillo, Mexican Social Security Institute, Mexico Raquel Evelyn Horowitz, Montefiore Medical Center, United States Updates Copyright 2026 Wang, Chen, Wang, Song and Zhang

This comprehensive literature search was conducted across multiple academic databases, including PubMed, Google Scholar, Web of Science, Scopus, Cochrane, and Science Direct