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W., Peck, B., and Schulze, A

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Reported side effects include: Nausea and queasiness , especially after meals during the first few weeks of dosing

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10.1042/BCJ20160510 144 TingN

discovered that crypotanshinone reversed 5-Fu resistance and boosted the inhibitory effect of 5-Fu in SGC7901/5-Fu cells by blocking the JAK/STAT3 signaling pathway, which in turn lowed the levels of Mcl-1, Bcl-xl, and Bcl-2 expression while raising Bax expression (183)