Hou L, Zhu ZZ, Zhang X, Nordio F, Bonzini M, Schwartz J, et al
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J Alzheimers Dis [Internet] J Alzheimers Dis
GLP-1 agonists do not require dose adjustment for renal function, but improved kidney perfusion from GLP-1-driven weight loss and blood pressure reduction may restore metformin eligibility over time
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This mechanism establishes hADSC-Exos as a viable cell-free regenerative therapy for POF, offering benefits such as low immunogenicity and enhanced safety compared to direct stem cell transplantation (Huang et al