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Pyruvate kinase M2 regulates Hif-1 activity and IL-1 induction and is a critical determinant of the warburg effect in LPS-activated macrophages
In brain tissue, misfolded proteins such as amyloid-beta and tau can sequester copper ions, creating local copper deficiency while simultaneously generating reactive oxygen species through aberrant metal-protein interactions
In human monocytic THP-1 cells, treatment with bilberry extract (BE), rich in anthocyanins, inhibited IFN- activation of STAT1 and STAT3 and lowered mRNA expression and/or secretion of MCP-1, TNF-, IL-6, and ICAM-1 (110)
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