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This is typically temporary and resolves on its own

Reduced inflammatory cytokine activity, improved microvascular integrity, and beneficial effects on pain modulation through peripheral and dopaminergic mechanisms are among the reported effects in animal studies

Second, the development of new drugs requires additional and more detailed preclinical and clinical studies to determine whether long-term use is biotoxic, whether the drug has adverse effects on other peripheral organs or whether the drug candidate has a real therapeutic effect on the patients

CagriSema was generally well-tolerated, with mild to moderate gastrointestinal adverse events, primarily nausea and vomiting [124]