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Kidney damage is its most prevalent effect on humans, but it may also affect fetal development and the immune system

Long-term safety data from post-marketing surveillance spans 40+ years

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Tumor cells that express PD-L1 on their surface hamper CD8+ T lymphocytes cytolytic effector activities

(65), the incidence of GC development in the high risk Chinese population, which was subjected to Hp eradication was unexpectedly reduced significantly only in a subgroup of Hp-carriers without pre-cancerous gastric lesions but not in those with pre-cancerous lesions