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To confirm the contribution of zonulin to early permeability changes in celiac disease, 20 patients on a gluten-free diet were randomized to a 3-day larazotide (12 mg once daily) or placebo treatment with a 2.5 g oral gluten challenge on the second day (96)

Scientific Context and Research Significance Synthetic peptides such as DSIP are valuable research tools because their defined molecular structures allow researchers to isolate specific biochemical signaling pathways

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