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A2018 studysuggests AP39 may protect cell structures that weaken over time

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For example, therapeutic use of an inhibitor of histone demethylase LSD1, which is overexpressed in skin epithelial cancer, drives notable increases in H3K4 methylation in the cells, thus leading to both premature epidermal differentiation and the repression of squamous cell carcinoma 34

doi: 10.12691/jfnr-3-10-1 10 Del RioDRodriguez-MateosASpencerJPTognoliniMBorgesGCrozierA

Ankyrin binding to (Na + + K + ) ATPase and implications for the organization of membrane domains in polarized cells Nature 1987