Jun 7 2017;18(6)doi:10.3390/ijms18061221
It plays a vital role in detoxification, immune function, and skin health
When drug-induced vasculitis is suspected, the causative agent should be discontinued immediately
Its unique combination of genetic similarity to humans, transparent embryos, and neuroanatomical parallels makes it a powerful platform for investigating AD mechanisms and testing therapeutic compounds
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Rigorous integration therefore requires method selection aligned with study structure, transparent handling of batch effects and missingness mechanisms, and validation strategies anchored to patient-relevant outcomes rather than intermediate surrogates