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While the significance of this finding remains to be determined, it is probably worth mentioning that a decrease in the number of large myelinated axons in rat caudal nerves was observed in all animals until day 30, with a markedly greater number in controls and fewer in injured rats that received BPC 157 treatment

Since primary therapy of sarcoidosis does not generally treat SFN, alternative therapies used for for other peripheral neuropathies are emplyed

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Understanding different resistance mechanisms to currently-existing inhibitors can provide new insights into combinatorial targeting of the driver oncoprotein and further downstream effectors to avoid or postpone the therapy resistance