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Figure 3), its basic actors, constitutive HSPA8 (also known as HSC70 and HSP73) and isoforms of inducible HSPA1, carry out most of the functions of the cytosolic response to protein misfolding or aggregation

They also had a 46.2% lower glutathione level than the controls

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Elevated free IGF-1 in epidemiological studies is associated with increased prostate, pre-menopausal breast, and colorectal cancer risk, though those associations involve chronically elevated endogenous IGF-1, not short-duration pharmaceutical use [8]

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Kung HF, Lee YC, Huang YL, Huang YR, Su YC, Tsai YH