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In the SURPASS clinical trial program, tirzepatide reduced HbA1c by 2.0-2.4% depending on dose, bringing the majority of participants to target levels below 7.0%

excessive B6 may cause nerve damage

It is not approved for human consumption outside of controlled, ethically approved clinical trials and laboratory environments

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Lifestyle Factors: Smoking: Smoking can accelerate skin ageing and contribute to skin discolouration due to decreased blood flow and oxygen delivery to the skin

Clinical features include weight loss, dystonia, stunted growth, and epilepsy, with an epilepsy incidence of 33.3%, most commonly presenting as generalized tonicclonic and myoclonic seizures (95)