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Rising prevalence of multiple sclerosis worldwide: insights from the Atlas of MS, third edition

A glutathione deficiency therefore leads to the activation of von Willebrand factor and the accumulation of ROS, which affect coagulation and platelet activation , impair endothelial function and predispose to the risk of thrombotic events , in particular hypercoagulation

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Microbiota and autophagy defect There is also interaction between intestinal microbiota and autophagy, which is closely related to the pathogenesis of thyroid autoimmune diseases