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Finally, we emphasize a critical knowledge gap regarding the role of the tissue environment as a modifier of glucocorticoid sensitivity and stress the need for integrated omics approaches to uncover tissue-specific epigenetic modifications associated with perinatal disease and clinical response to glucocorticoids

In Parkinson's disease, oxidative stress plays a role in damaging the neurons that produce dopamine, a crucial brain chemical

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Toxicology 1992;76:7987

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