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Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit

As discussed above, excessive production of pro-inflammatory mediators and free radicals may cause damage to the nervous tissue, impairing axonal conductivity, causing retrograde neuronal death, and developing the conditions for neuropathic pain [6]

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1) and lower SOD (Mann-Whitney, Z = 2.18, P = 0.013

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DOI: 10.1016/j.freeradbiomed.2019.02.009