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Enantiomers were separated and according to computational modeling the inhibitory capacity of the compounds were attributed to the S -configuration of the spiro-oxindole dihydroquinazolinones

Oct 2002;47(10):821-4

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10.1016/j.cgh.2020.02.027 Summary Keywords intestinal permeability, GI diseases, coeliac disease, chronic liver disease, inflammatory bowel disease, bile acid malabsorption, paracellular route, transcellular route Citation Vanuytsel T, Tack J and Farre R (2021) The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation