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The intervals themselves are free from signs of disease. His observations were later included in the definition of the periodic syndrome of childhood described by Wyllie and Schlesinger in 1933

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The pathogenic triad Researchers now describe the core of psoriasis pathology as a pathogenic triad consisting of dendritic cells, TH17 cells, and keratinocytes

doi: 10.1007/s10903-010-9330-z 111 BernardesJGBFernandesMRRodriguesJCGVinagreLWMSPastanaLFDobbinEAFet al