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RNA polymerase II-associated factor 1 regulates stem cell features of pancreatic cancer cells, independently of the PAF1 complex, via interactions with PHF5A and DDX3

These findings established EV-derived VDAC1 as a critical mediator of PTX resistance and proposed targeting EV-derived VDAC1 as a novel therapeutic strategy to overcome chemoresistance in GC

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Most cell lysates and tissue ho- mogenates should also be compatible

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The injection vehicle is carefully selected to ensure compatibility with both active ingredients while maintaining appropriate pH, osmolality, and other physical characteristics necessary for subcutaneous administration