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That's in addition to, as mentioned by Gambit, excess alcohol causing issues with the liver which is the primary bodily store of B12

Unfortunately it later turned out that oral bioavailability in humans is dramatically lower than in rodents

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As you know, I am not a fan of the drops now that I have experienced the huge difference between them and the injections

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DNA Synthesis B12 (as methylcobalamin) is a cofactor for methionine synthase, the enzyme that converts homocysteine to methionine and enables normal DNA synthesis