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Eisenberg DS, Sawaya MR (2017) Structural studies of amyloid proteins at the molecular level
results depend mainly on the overall plan
Mechanistically, at very low, non-toxic concentrations, the peptide stimulates collagen, glycosaminoglycans, and proteoglycans such as decorin, while modulating the matrix metalloproteinases involved in extracellular matrix remodeling during healing
Several lines of evidence demonstrate memory deficits concurrent with copper deposition in the choroid plexus, astrocyte swelling (Alzheimer type II cells), astrogliosis and neuronal degeneration in the cerebral cortex, and augmented levels of copper and zinc in the hippocampus of chronically copper-intoxicated rats [337]
J., Asara, J