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Oligomerization [edit] Glutathione S-transferases form homodimers, but in eukaryotes can also form heterodimers of the A1 and A2 or YC1 and YC2 subunits

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Maintenance dosing schedules are less often than the first doses, usually monthly

doi: 10.1073/pnas.1415518111 127 WangYBiRQuanFCaoQLinYYueCet al

The drug binds to PXR, forming an activated complex, and subsequently combines with the retinoid X receptor (RXR) to form a heterodimer that targets a DNA response element, enhancing CYP3A4 gene transcription