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Considering the blood-ocular barrier as well as the lens nuclear barrier (152), an appropriate drug delivery system is also a vital subject for lens drug research

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Because of ubiquitination and subsequent proteolysis, Nrf2 turns over rapidly with a half-life of 715 min, which increases to 30100 min in the presence of oxidative or electrophilic stress (McMahon et al

Valentino MA, Lin JE, Waldman SA