MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases Mohtashami Z, Singh MK, Salimiaghdam N, Ozgul M, Kenney MC (2022)
doi: 10.1177/1470320309352800 83 Martinez-FierroMLLeachRJGomez-GuerraLSGarza-GuajardoRJohnson-PaisTBeutenJet al
The compound works through the same NNMT inhibition mechanism in both sexes, though dosing may need adjustment based on body weight
Preclinical models examining cellular adaptation and response to experimentally induced stress or injury
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It does this by blocking the enzyme tyrosinase, which is involved in melanin production