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Neurologic complications are not always associated with megaloblastic anemia and are the only clinical symptom of vitamin B 12 deficiency in about 25% of cases (21)

Compared with the HCD group, the HCD + ALC group exhibited significantly decreased hepatic protein levels of SREBP2 (Figure 3B), 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR

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This is the same receptor activated by natural GHRH, the hypothalamic peptide that controls growth hormone secretion. By mimicking the active region of GHRH, CJC-1295 stimulates the pituitary through the bodys natural GH-release pathway rather than bypassing it with exogenous GH

Enhancing bioavailability of noradrenaline or adrenergic responsiveness of astrocytes could be a valid therapeutic strategy