Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007
For patients whose prior B12 supplementation hasn't worked, injection is the solution not a higher oral dose
Injections may be recommended when: There is impaired absorption (for example, pernicious anaemia)
May present with bloody stool, urgency, and perianal disease
The MHRA advises checking B12 levels in patients taking metformin who develop symptoms of deficiency or have risk factors, with periodic monitoring in at-risk patients
Verified Answer is this the same as b12 used for humans