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Mild sonication may be used if needed

The clinical significance arises when B12 is elevated without a clear exogenous explanation

CAS Number: 68-19-9 (Cyanocobalamin reference form) Molecular Formula: C63H88CoN14O14P Molecular Weight: ~1355.38 g/mol Compound Classification: Naturally occurring cobalt-containing corrinoid vitamin Specifications Form: Aqueous solution Concentration: 1000 g/mL (nominal) Vitamin B-12 Volume: 10 mL Filtration: 0.2 m sterile membrane Preservative: 0.9% Benzyl Alcohol Container: Sterile glass vial Appearance: Red solution Purity: Manufactured to defined specification (98% assay cyanocobalamin

We consider the severity of the disease, specific organ involvement, and how each individual has responded to other therapies before recommending infusion treatment

Hydroxocobalamin and Tiaminal B12 might need special prescriptions due to their unique properties

Chapman LE, Darling AL, Brown JE