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Bacterial translocation typically occurs in small quantities and is regulated by liver immune cells that uphold immune tolerance toward the components of the commensal microbiota
This suggests that drugs targeting IFN-, IL-1 or IL-6 could potentially be useful for treating patients who do not respond to anti-TNF therapy
Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
This approach helps minimize the risk of side effects such as nausea, vomiting, diarrhea, or bloating, and makes the treatment more sustainable