Large-scale gene expression in bone marrow mesenchymal stem cells: a putative role for COL10A1 in osteoarthritis
Generally, patients receiving consistent injections report improved quality of life
Benefits (Research Focus) Studied as a high-affinity potentiator of hepatocyte growth factor (HGF) signaling (Kd 65 pM) Investigated for c-Met receptor activation and downstream signal transduction Explored for functional dendritic spine formation and synaptic connectivity Examined in rodent models of Alzheimers-like cognitive impairment Researched as a structurally optimized angiotensin IV / AT4 receptor analog What Researchers Look At HGF / c-Met receptor binding affinity and phosphorylation cascades Dendritic spine density and synaptic protein expression in hippocampal cultures Long-term potentiation (LTP) and electrophysiological endpoints in brain slice models Cognitive performance in aged and AD-model rodents (Morris water maze, object recognition) Comparative neurotrophic mimetic pharmacology versus BDNF and NGF Quick Specs Form: Gelatin capsule Strength: 5 mg / capsule Quantity: 30 capsules per bottle Excipient: Microcrystalline cellulose (MCC) pharmaceutical-grade filler Purity: 99% Storage: Store in a cool, dry, dark place Identity Basics Compound: Dihexa Synonyms: PNB-0408
There are clinical trials and there are anecdotal reports, but they are not substantial
These are FDA-approved finished drug products
Clinical trial safety data analyzed: 0.3% pancreatitis, 1.4% gallbladder events, 11.2% discontinuation
