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A fatty acid with fewer than six carbon atoms (for example, acetate, propionate and butyrate) that is the end-product of fermentation of dietary fibres by the anaerobic intestinal microbiota and acts as a signal molecule in the control of mammalian energy metabolism

In cells, it increases expression of canonical ERR target genes and enhances mitochondrial respiration

Methods 70 SapplP

Identifying patient subgroups that are sensitive to ferroptosis-targeting agents and determining the optimal treatment populations remain unresolved issues

Phase IIb trials failed efficacy endpoints

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