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TGF-1-activated cancer-associated fibroblasts promote breast cancer invasion, metastasis and epithelial-mesenchymal transition by autophagy or overexpression of FAP-

10.1186/s12866-015-0462-0 23 Casado-VelaJ.SellsS.MartnezR

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GHK-Cu is a tripeptide three amino acids (glycine, histidine, lysine) with a high-affinity binding site for copper(II) ions

This also causes increased TNF- release, which ultimately leads to the containment of M

This matters because even minor sequence variations can alter receptor binding affinity and downstream signaling effects