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If your solution is foamy after mixing, you were too aggressive

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Dihexa (PNB-0408) (2-4mg/kg;b.wt.;16 weeks) is promising candidates for adjunct therapies to promote limb functional recovery after surgical nerve repair, and have implications in peripheral nerve injury and limb transplantation [8]

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PLoS Negl Trop Dis 6:e1726