We further performed doxycycline-inducible expression of oxygen-dependent NADPH oxidase (NOX) in the cytosol (TPNOX) or mitochondria (mitoTPNOX) to deplete compartmentalized NADPH, as described previously 30 , and tested the cellular sensitivity to glucose starvation (Extended Data Fig
Journal of Materials Chemistry B
Homologous recombination events were confirmed by Southern blot analysis, and positive clones were injected into blastocysts derived from C57Bl/6 mice
If the patient is suspected to be sensitive to cobalt or other components of cobalamin, an intradermal test dose is recommended
Among the evaluated samples, sample A displayed the highest B12 concentration (3.92 g/100 g), suggesting a potential advantage in mitigating deficiency-related outcomes
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