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Furthermore, results from a phase II clinical trial conducted on AD patients demonstrated that NR administration was associated with favorable alterations in cerebrospinal fluid biomarkers indicative of improved mitochondrial function [23]

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Patients with Fitzpatrick IV-VI skin should be monitored for potential irritation during initial use, particularly in combination with other actives, and formulations should be pH-controlled (pH 3.5 or lower for efficacy without excessive irritation)

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Final dosing is always determined by your provider