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The seed coatings based on AGS and SiNPs further induced a SiNP dose-dependent significant decrease in ROS level that became lower than the one in the absence of salt ( Figures 11A-C )

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a , Mitochondrial abundance of GSH in HEK-293T SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA treated with GSH (5 mM) or GSHee (5 mM) for 24 h

Similar approaches have successfully generated cardiac spheroids using rat neonatal ventricular cardiomyocytes, human dermal fibroblasts, and human coronary microartery ECs in ultra-low attachment plates [253], as well as spheroids composed of human iPSC-derived cardiomyocytes, human cardiac fibroblasts, and HUVECs in an ultra-low attachment hanging drop system [254]