~ AlphaMD You're doing everything right on paper, but something is still off
[ref][ref] Iron regulation: While the full details arent yet known, pantothenic acid and the PANK2 enzyme interact with iron regulation, with low B5 increasing iron accumulation.[ref] Symptoms of Pantothenic Acid Deficiency: While uncommon, a deficiency of vitamin B5 due to genetic mutations or malnutrition can cause:[ref][ref] fatigue, irritability, listlessness burning feet numbness in the hands and feet paresthesia and muscle cramps restlessness, sleep disturbances nausea, vomiting, and abdominal cramps Mice that are deficient in pantothenic acid develop graying of the fur, movement disorder, and skin irritation.[ref] Absorption and transport: Vitamin B5 is readily absorbed from foods as they are broken down in the intestines
Although most people assume anemia is only an iron issue, there are a number of nutrients that play a role
In an 8-week open-label trial, a group of researchers evaluated the effect of Clostridium butyricum MIYAIRI 588 (CBM588) in patients with treatment-resistant MMD in an open-label study (Miyaoka et al., 2018)
Neulasta, a pegylated granulocyte-colony stimulating factor, reduces the incidence of infection in patients receiving myelosuppressive chemotherapy by stimulating neutrophil production [109,110,111]
Mller B, Schmidt J, Mehlhorn H