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Consequently, there is an accumulation of lipid ROS in vivo, which leads to DNA (48), protein (49) and lipid damage (50), ultimately resulting in cell death
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Subsequently, the efficient GSH-mediated release of DOX into the cytosol was observed (Figure 2) ( FIGURE 2 Thermo-responsive drug delivery Thermo-responsive hydrogels are relatively the most researched responsive hydrogel systems because they show exclusive properties in controlled drug delivery systems
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