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Inflammatory diseases Inflammation, deemed a protective response to pathogens, irritation, and injury 131 , can effectively remove invading pathogens and maintain tissue integrity by releasing inflammatory mediators, inducing inflammatory cell migration and aggregation 132

IGF-1 DES exhibits moderate side effects, low oral and excellent subcutaneous bioavailability in mice

Terazawa S, Nakajima H, Shingo M, Niwano T, Imokawa G (2012) Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletionindependent manner

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Kidney problems, gallstones, eye damage, bone or joint injury, and slow development are risk factors